Pulmonary function testing in patients with neuromuscular disease. Issue 4 (8th December 2020)

• Record Type: Journal Article
• Authors: Miller, Kristen; Mayer, Oscar H.
• Other Names: Birnkant David guestEditor.; Cripe Linda guestEditor.
• Is Part Of: Pediatric pulmonology. Volume 56:Issue 4(2021)
• Page Start: 693
• Page End: 699
• Publication Date: 2020-12-08
• Subjects: neuromuscular disorders -- pulmonary function testing (PFT); Pediatric respiratory diseases -- Periodicals; Pediatrics -- Periodicals; 618.922
• DOI: 10.1002/ppul.25182
• Languages: English
• ISSNs: 8755-6863

Abstract

Abstract: Progressive neuromuscular disease leads to muscle weakness or failure that produces loss of pulmonary function and clinical respiratory morbidity. Tracking pulmonary function in a practical and effective way is very important because it can help identify a stage of disease when a morbidity, such as inadequate airway clearance or respiratory failure, may be present. There are four general categories of pulmonary function outcome measures such as volume, flow, pressure, and gas exchange. These outcome measures have variable precision and accuracy in predicting clinical change, and practicality in performing them relative to age and condition. It is widely recommended to follow multiple measurements longitudinally and create an accurate and timely clinical picture. This manuscript will review the most commonly used and most practical measures for use in clinical practice and how they can help to assess morbidity, disease state, and help optimize patient management.