Recent Progress in Palladium‐Catalyzed Radical Reactions. Issue 6 (3rd February 2021)

• Record Type: Journal Article
• Authors: Sun, Xi; Dong, Xu; Liu, Hui; Liu, Yuying
• Is Part Of: Advanced synthesis & catalysis. Volume 363:Issue 6(2021)
• Page Start: 1527
• Page End: 1558
• Publication Date: 2021-02-03
• Subjects: Palladium catalysis -- Radical -- Single electron transfer -- C−H activation -- Coupling reactions; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202001315
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: In recent years, great improvements have been made on palladium‐catalyzed radical reactions. Emerging elegant methodologies of radical involved palladium‐catalyzed transformations provide more and more effective strategies for the construction of complex heterocyclic compounds and applications in drug discovery. It is universally known that Pd(0)/(II)/(IV)‐mediated reactions usually undergo two‐electron transfer processes, while the Pd(I) and Pd(III) involved reactions usually occur via single electron transfer processes. Since our review on palladium radical was published, numurous methodolgies involving palladium radical have sprung up in the past five years. This review further summarized the up‐to‐date transformations toward palladium radical from 2015. For most of these catalytic cycles strategies, plausible mechanisms are demonstrated in detail to give better insight for chemists in need. Abstract :