Efficient demethylation of aromatic methyl ethers with HCl in water. Issue 5 (26th February 2021)
- Record Type:
- Journal Article
- Title:
- Efficient demethylation of aromatic methyl ethers with HCl in water. Issue 5 (26th February 2021)
- Main Title:
- Efficient demethylation of aromatic methyl ethers with HCl in water
- Authors:
- Bomon, Jeroen
Bal, Mathias
Achar, Tapas Kumar
Sergeyev, Sergey
Wu, Xian
Wambacq, Ben
Lemière, Filip
Sels, Bert F.
Maes, Bert U. W. - Abstract:
- Abstract : A method for the cleavage of aryl alkyl ethers is presented, involving hot pressurized water and catalytic mineral acid. The protocol is applicable on a variety of (biorenewable) substrates, not requiring mass-intensive work-up. Abstract : A green, efficient and cheap demethylation reaction of aromatic methyl ethers with mineral acid (HCl or H2 SO4 ) as a catalyst in high temperature pressurized water provided the corresponding aromatic alcohols (phenols, catechols, pyrogallols) in high yield. 4-Propylguaiacol was chosen as a model, given the various applications of the 4-propylcatechol reaction product. This demethylation reaction could be easily scaled and biorenewable 4-propylguaiacol from wood and clove oil could also be applied as a feedstock. Greenness of the developed method versus state-of-the-art demethylation reactions was assessed by performing a quantitative and qualitative Green Metrics analysis. Versatility of the method was shown on a variety of aromatic methyl ethers containing (biorenewable) substrates, yielding up to 99% of the corresponding aromatic alcohols, in most cases just requiring simple extraction as work-up.
- Is Part Of:
- Green chemistry. Volume 23:Issue 5(2021)
- Journal:
- Green chemistry
- Issue:
- Volume 23:Issue 5(2021)
- Issue Display:
- Volume 23, Issue 5 (2021)
- Year:
- 2021
- Volume:
- 23
- Issue:
- 5
- Issue Sort Value:
- 2021-0023-0005-0000
- Page Start:
- 1995
- Page End:
- 2009
- Publication Date:
- 2021-02-26
- Subjects:
- Environmental chemistry -- Industrial applications -- Periodicals
Environmental management -- Periodicals
660 - Journal URLs:
- http://www.rsc.org/ ↗
http://pubs.rsc.org/en/journals/journalissues/gc#issueid=gc016010&type=current&issnprint=1463-9262 ↗ - DOI:
- 10.1039/d0gc04268d ↗
- Languages:
- English
- ISSNs:
- 1463-9262
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4214.935500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 16140.xml