Metabolic adaptation of Pseudomonas pseudoalcaligenes CECT5344 to cyanide: role of malate–quinone oxidoreductases, aconitase and fumarase isoenzymes. (21st November 2011)

• Record Type: Journal Article
• Authors: Igeño, M. Isabel; Becerra, Gracia; Guijo, M. Isabel; Merchán, Faustino; Blasco, Rafael
• Is Part Of: Biochemical Society transactions. Volume 39:Number 6(2011)
• Page Start: 1849
• Page End: 1853
• Publication Date: 2011-11-21
• Subjects: aconitase -- biodegradation -- cyanide -- fumarase -- malate–quinone oxidoreductase -- Pseudomonas pseudoalcaligenes; Biochemistry -- Congresses; 572
• DOI: 10.1042/BST20110714
• Languages: English
• ISSNs: 0300-5127

Abstract

Abstract : In general, the biodegradation of a toxic compound by a micro-organism requires the concurrence of, at least, two features in the biological system: first, the capability of the micro-organism to metabolize the toxic compound, and secondly, the capacity to resist its toxic effect. Pseudomonas pseudoalcaligenes CECT5344 is a bacterium used in the biodegradation of cyanide because it is capable to use it as a nitrogen source. The present review is mainly focused on the putative role of iron-containing enzymes of the tricarboxylic acid cycle in cyanide resistance by P. pseudoalcaligenes CECT5344.