Caveolins and membrane cholesterol. (1st February 2004)

• Record Type: Journal Article
• Authors: Ikonen, E.; Heino, S.; Lusa, S.
• Is Part Of: Biochemical Society transactions. Volume 32:Number 1(2004)
• Page Start: 121
• Page End: 123
• Publication Date: 2004-02-01
• Subjects: caveolae -- cholesterol -- intracellular transport -- membrane domain; Biochemistry -- Congresses; 572
• DOI: 10.1042/bst0320121
• Languages: English
• ISSNs: 0300-5127

Abstract

Abstract : Caveolae (small plasma membrane invaginations) and their coat proteins, caveolins, have attracted the attention of researchers in diverse fields, including cell biology, cardiovascular and cancer research. The tight association between caveolin and cholesterol governs the biochemical behaviour of caveolae and is emerging as an important characteristic in a number of processes assigned to these multifunctional organelles. In this review, selected aspects of the caveolin–cholesterol association and its potential functional implications are discussed.