Iron-catalyzed cross-dehydrogenative C–H amidation of benzofurans and benzothiophenes with anilines. Issue 7 (4th February 2021)

• Record Type: Journal Article
• Authors: Ni, Yang; Wan, Xiang; Zuo, Honghua; Bashir, Muhammad Adnan; Liu, Yu; Yu, Huaibin; Liao, Rong-Zhen; Wu, Guojiao; Zhong, Fangrui
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 7(2021)
• Page Start: 1490
• Page End: 1495
• Publication Date: 2021-02-04
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d0qo01651a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : An efficient iron-catalyzed radical cross-dehydrogenative aromatic C–H amidation provides a straightforward access to structurally diverse diarylamine derivatives incorporating benzofuran/benzothiophene motifs. Abstract : An efficient iron-catalyzed cross-dehydrogenative aromatic C–H amidation using DDQ as an oxidant under mild conditions is reported, providing a straightforward access to structurally diverse diarylamine derivatives incorporating benzofuran/benzothiophene motifs. Mechanistic studies indicated that a nitrogen-centered anilino radical is involved in the C–N bond formation.