Effects of exposure to high potassium concentration on the longitudinal muscle-myenteric plexus preparation from guinea-pig. Issue 2 (February 1986)

• Record Type: Journal Article
• Authors: Aleixandre, M. A.; Ayala, E.; Garcia de Jalón, P.
• Is Part Of: Bioscience reports. Volume 6:Issue 2(1986)
• Page Start: 215
• Page End: 220
• Publication Date: 1986-02
• Subjects: K+ -- muscle -- myenteric plexus; Molecular biology -- Periodicals; Cytology -- Periodicals; 572.8
• DOI: 10.1007/BF01115009
• Languages: English
• ISSNs: 0144-8463

Abstract

Abstract : The effect of potassium on the longitudinal muscle-myenteric plexus (LM-MP) preparation from guinea-pig was studied. The strips were exposed to elevated K + (30 m M, 60 m M, 90 m M, 120 m M or 150 m M ). A phasic contraction of the LM-MP was caused by 10m M K + or 15 m M K + followed by an increase of the contractile activity probably due to the increase in acetylcholine release. A higher molarity of K + produces more marked depolarization in the LM-MP and above 22m M K + tetanizing effects were observed. We attempted to demonstrate that opiate-like material could be released when the tissue was exposed to more than 30 m M K + even though several different neurotransmitters could be liberated by elevated K + molarities.