Polyamine metabolism and cancer prevention. (20th March 2007)
- Record Type:
- Journal Article
- Title:
- Polyamine metabolism and cancer prevention. (20th March 2007)
- Main Title:
- Polyamine metabolism and cancer prevention
- Authors:
- Saunders, F.R.
Wallace, H.M. - Abstract:
- Abstract : Colorectal cancer is one of a number of cancers that may be amenable to prevention. The NSAIDs (non-steroidal anti-inflammatory drugs) have been shown to be effective chemopreventative agents in humans, but their mechanism of action is not clear. The polyamines are cellular polycations that are essential for cell growth and are overproduced in cancer cells. It is our hypothesis that inhibition of polyamine metabolism is an integral part of the mechanism of cancer prevention mediated by NSAIDs.
- Is Part Of:
- Biochemical Society transactions. Volume 35:Number 2(2007)
- Journal:
- Biochemical Society transactions
- Issue:
- Volume 35:Number 2(2007)
- Issue Display:
- Volume 35, Issue 2 (2007)
- Year:
- 2007
- Volume:
- 35
- Issue:
- 2
- Issue Sort Value:
- 2007-0035-0002-0000
- Page Start:
- 364
- Page End:
- 368
- Publication Date:
- 2007-03-20
- Subjects:
- chemoprevention -- colorectal cancer -- cytotoxicity -- non-steroidal anti-inflammatory drug (NSAID) -- polyamine
Biochemistry -- Congresses
572 - Journal URLs:
- https://portlandpress.com/biochemsoctrans ↗
- DOI:
- 10.1042/BST0350364 ↗
- Languages:
- English
- ISSNs:
- 0300-5127
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 16155.xml