Regulation of TRPML1 function. (1st June 2015)
- Record Type:
- Journal Article
- Title:
- Regulation of TRPML1 function. (1st June 2015)
- Main Title:
- Regulation of TRPML1 function
- Authors:
- Waller-Evans, Helen
Lloyd-Evans, Emyr - Abstract:
- Abstract : TRPML1 is a ubiquitously expressed cation channel found on lysosomes and late endosomes. Mutations in TRPML1 cause mucolipidosis type IV and it has been implicated in Alzheimer's disease and HIV. However, the mechanisms by which TRPML1 activity is regulated are not well understood. This review summarizes the current understanding of TRPML1 activation and regulation.
- Is Part Of:
- Biochemical Society transactions. Volume 43:Number 3(2015)
- Journal:
- Biochemical Society transactions
- Issue:
- Volume 43:Number 3(2015)
- Issue Display:
- Volume 43, Issue 3 (2015)
- Year:
- 2015
- Volume:
- 43
- Issue:
- 3
- Issue Sort Value:
- 2015-0043-0003-0000
- Page Start:
- 442
- Page End:
- 446
- Publication Date:
- 2015-06-01
- Subjects:
- ion selectivity -- pH regulation -- PtdIns(3 -- 5)P2 -- mucolipin 1 -- TRPML1
Biochemistry -- Congresses
572 - Journal URLs:
- https://portlandpress.com/biochemsoctrans ↗
- DOI:
- 10.1042/BST20140311 ↗
- Languages:
- English
- ISSNs:
- 0300-5127
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 16152.xml