The acceleration of ageing in older patients with cancer. Issue 3 (April 2021)

• Record Type: Journal Article
• Authors: Muhandiramge, Jaidyn; Orchard, Suzanne; Haydon, Andrew; Zalcberg, John
• Is Part Of: Journal of geriatric oncology. Volume 12:Issue 3(2021)
• Page Start: 343
• Page End: 351
• Publication Date: 2021-04
• Subjects: Cancer -- Ageing -- Accelerated ageing -- Older patients -- Cognitive decline -- Frailty -- Functional decline -- Chronic disease; Geriatric oncology -- Periodicals; Neoplasms -- Periodicals; Aged -- Periodicals; Geriatric oncology; Electronic journals; Periodicals; 618.976994005
• DOI: 10.1016/j.jgo.2020.09.010
• Languages: English
• ISSNs: 1879-4068

Abstract

Abstract: Older cancer survivors may experience ageing at an accelerated rate when compared to their similar-aged, cancer-free counterparts. Ageing is undoubtedly a significant risk factor for cancer. There is evidence to suggest, however, that this relationship may in fact be bidirectional, with cancer and its treatments contributing to the ageing process. In this review, we outline the current literature linking cancer and anti-cancer therapy to adverse ageing outcomes and explore what additional research is needed in order to conclusively define cancer and its treatment as an accelerator of ageing.