Lyn tyrosyl kinase binds to the human cAMP-specific phosphodiesterase pde46 (HSPDE4A4B) and causes a conformational change in its catalytic unit ¶. (June 1999) - McPhee, I; Yarwood, S.J.; Huston, E.; Scotland, G.; Beard, M.; Ross, A.H.; Houslay, M.D.