Metalloregulatory proteins and nitric oxide signalling in bacteria. (19th November 2008)

• Record Type: Journal Article
• Authors: Spiro, Stephen
• Is Part Of: Biochemical Society transactions. Volume 36:Number 6(2008)
• Page Start: 1160
• Page End: 1164
• Publication Date: 2008-11-19
• Subjects: bacterium -- metalloregulatory protein -- nitric oxide -- regulatory protein -- transcription -- transition metal cofactor; Biochemistry -- Congresses; 572
• DOI: 10.1042/BST0361160
• Languages: English
• ISSNs: 0300-5127

Abstract

Abstract : Bacterial gene regulators containing transition metal cofactors that function as binding sites for small ligands were first described in the 1990s. Since then, numerous metal-containing regulators have been discovered, and our knowledge of the diversity of proteins, their cofactors and the signals that they sense has greatly increased. The present article reviews recent developments, with a particular focus on bacterial sensors of nitric oxide.