Incidence and associated factors of emergence agitation after general anesthesia and surgery among pediatric patients: A prospective follow-up study. (2020)

• Record Type: Journal Article
• Authors: Eshetie, Denberu; Getinet, Habtamu; Abdissa, Zewditu; Mollalign, Mamaru
• Is Part Of: International journal of surgery open. Volume 27(2020)
• Page Start: 25
• Page End: 31
• Publication Date: 2020
• Subjects: Emergence agitation -- Pediatric -- General anesthesia -- Surgery -- Incidence -- Associated factor; Surgery -- Periodicals; 617.005
• DOI: 10.1016/j.ijso.2020.10.005
• Languages: English
• ISSNs: 2405-8572

Abstract

Abstract: Introduction: Emergence agitation is one of the significant anesthetic and surgery-related complications. It is usually short-lived but causes self-injury during agitation and it led to parental anxiety. This study was aimed to assess incidence and factors associated with emergence agitation after general anesthesia and surgery among pediatric patients at University of Gondar specialized hospital. Methods: A prospective follow-up study conducted on 153 pediatric patients aged 2–9 years who were operated from first February to April 30, 2019. Emergence agitation was recorded by the pediatrics anesthesia emergence delirium scale. Descriptive statistics performed to determine the incidence. To identify the associated factors multi-variable binary logistic regression was held, and a p-value <0.05 was considered as significant. Results: Emergence agitation was experienced on eighty (52.3%) children with a mean and standard deviation of 12 ± 5.9 min of duration. Among agitated children, 8 (10%) of them developed adverse events related to agitation. Difficult parental separation behaviour (AOR = 2.688, 95% CI = 1.131–6.39), children aged 2–5 years (AOR = 2.688, 95% CI = 1.131–6.3925), isoflurane maintenance (AOR = 4.001, 95% CI = 1.733–9.234) and propofol administration after maintenance closure (AOR = 0.145, 95% CI = 0.030–0.695) were significantly associated with agitation. Conclusion: Being a preschool child, difficult parental separation and isoflurane maintenance were associated with emergence agitation. But propofol administration after maintenance closure was found to be protective. So, agitation should be assessed and detected in the postoperative period and efforts should apply to prevent emergence agitation. Highlights: The incidence of emergence agitation among pediatrics patients still high. Isoflurane is a predictor of emergence agitation. Propofol administration after maintenance closure near the end of surgery found to be protective of emergence agitation.