Thoracic endometriosis presented as catamental hemoptysis: a case series of a rare disease. (3rd April 2021)

• Record Type: Journal Article
• Authors: Dai, Yi; Li, Meng-Hui; Liu, Yong-Jian; Liu, Bing; Wu, Yu-Shi; Lang, Jing-He; Zhang, Zhen-Yu; Leng, Jin-Hua
• Is Part Of: Current medical research and opinion. Volume 37:Number 4(2021)
• Page Start: 685
• Page End: 691
• Publication Date: 2021-04-03
• Subjects: Catamenial hemoptysis -- COC -- GnRHa hormonal treatment -- thoracic endometriosis; Clinical medicine -- Periodicals; Therapeutics -- Periodicals; 615.5
• DOI: 10.1080/03007995.2021.1885363
• Languages: English
• ISSNs: 0300-7995

Abstract

Abstract: Objective: Thoracic endometriosis syndrome (TES) is a rare disease in which a functioning endometrial tissue is observed in the pleura, lung, parenchyma, airways, and/or diaphragm. The optimal management of this disease remains a matter of debate. We aimed to report TES cases and their effective hormonal treatment and management. Methods: In this retrospective study, women presented as catamenial hemoptysis (CH) diagnosed with thoracic endometriosis were included. The main outcome of measure was cessation or recurrence of the clinical manifestations of thoracic endometriosis. Results: The mean onset age of the 14 patients was 30.21 ± 5.40 years. CH was characteristic symptom of these patients. All patients underwent chest computed tomography (CT) scan during menstruation and 2 or 3 weeks after menstruation, which showed the obvious shrinking or disappearance of the lesions. All of the patients were given Gonadotropin releasing hormone agonists (GnRHa) for 3 to 6 months, eleven of them were administered with combined oral contraceptives (COC) cyclically after GnRHa. The median follow-up duration was 24 months. Hemoptysis recurrence was observed in one patient. Conclusions: CH is a rare clinical entity of thoracic endometriosis, the change of CT images during and after menstruation or the response to GnRHa were helpful for accurate diagnosis. Hormonal treatment with GnRHa followed by COCs cyclically could be employed for efficient management of thoracic endometriosis.