Computer modeling and in vitro experimental study of water-cooled microwave ablation array. Issue 1 (1st February 2021)

• Record Type: Journal Article
• Authors: Chen, Dui-Dui; Du, Yu-Xin; Chen, Zu-Bing; Lang, Liang; Ye, Zi; Yang, Qiang; Shen, Shi-Qiang; Lei, Zhen-Yu; Zhang, Si-Qi
• Is Part Of: Minimally invasive therapy & allied technologies. Volume 30:Issue 1(2021)
• Page Start: 12
• Page End: 20
• Publication Date: 2021-02-01
• Subjects: Finite-element method (FEM) -- microwave ablation -- microwave ablation device -- tissue-mimicking phantom; Endoscopy -- Periodicals; Interventional radiology -- Periodicals; Endoscopic surgery -- Periodicals; 617.05
• DOI: 10.1080/13645706.2019.1674878
• Languages: English
• ISSNs: 1364-5706

Abstract

Abstract: Introduction: Microwaves (MWs) quickly deliver relatively high temperatures into tumors and cover a large ablation zone. We present a research protocol for using water-cooled double-needle MW ablation arrays for tumor ablation here. Material and methods: Our research program includes computer modeling, tissue-mimicking phantom experiments, and in vitro swine liver experiments. The computer modeling is based on the finite element method (FEM) to evaluate ablation temperature distributions. In tissue-mimicking phantom and in vitro swine liver ablation experiments, the performances of the new device and the single-needle MW device currently used in clinical practice are compared. Results: FEM shows that the maximum transverse ablation diameter (MTAD) is 4.2 cm at 100 W output and 300 s (assessed at the 50 °C isotherm). In the tissue-mimicking phantom, the MTDA is 2.6 cm at 50 W and 300 s in single-needle MW ablation, and 4 cm in double needle MW ablation array. In in vitro swine liver experiments, the MTAD is 2.820 ± 0.127 cm at 100 W and 300 s in single-needle MW ablation, and 3.847 ± 0.103 cm in MW ablation array. Conclusion: A new type of water-cooled MW ablation array is designed and tested, and has potential advantages over currently used devices.