Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients. (7th June 2020)

• Record Type: Journal Article
• Authors: Long, Dustin R; Gombar, Saurabh; Hogan, Catherine A; Greninger, Alexander L; O'Reilly-Shah, Vikas; Bryson-Cahn, Chloe; Stevens, Bryan; Rustagi, Arjun; Jerome, Keith R; Kong, Christina S; Zehnder, James; Shah, Nigam H; Weiss, Noel S; Pinsky, Benjamin A; Sunshine, Jacob E
• Is Part Of: Clinical infectious diseases. Volume 72:Number 2(2021)
• Page Start: 323
• Page End: 326
• Publication Date: 2020-06-07
• Subjects: COVID-19 -- SARS-CoV-2 -- RT-PCR -- test characteristics -- nasopharyngeal; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciaa722
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Using data for 20 912 patients from 2 large academic health systems, we analyzed the frequency of severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction test discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and was similar across institutions.