A Surviving Child from Acute Liver Failure after an Ingestion of Cassia occidentalis Seeds. (23rd November 2020)

• Record Type: Journal Article
• Authors: Getsuwan, Songpon; Tanpowpong, Pornthep; Trakulsrichai, Satariya; Sornmayura, Pattana; Treepongkaruna, Suporn
• Is Part Of: Journal of tropical pediatrics. Volume 67:Number 1(2021)
• Publication Date: 2020-11-23
• Subjects: Cassia occidentalis -- acute liver failure -- hepatic encephalopathy -- hepatomyoencephalopathy -- N-acetylcysteine -- renal tubular acidosis; Pediatrics -- Periodicals; Tropical medicine -- Periodicals; Pediatrics -- Periodicals; Tropical Medicine -- Periodicals; Environmental Health -- Periodicals; Infant; Child; 618.929883
• DOI: 10.1093/tropej/fmaa087
• Languages: English
• ISSNs: 0142-6338

Abstract

Abstract: Cassia occidentalis toxicity is thought to be uncommon; however, several cases have been described with acute hepatomyoencephalopathy with a high-mortality rate. We report a previously healthy, 2-year-old girl who developed acute liver failure after fresh seed ingestion. Without a specific antidote, we decided to implement supportive measures and medications including lactulose, sodium benzoate and N-acetylcysteine. The patient also experienced with cardiogenic shock and transient distal renal tubular acidosis, which were all spontaneously resolved. The liver chemistries returned to normal 3 months after the ingestion, without receiving liver assisted device or liver transplantation.