Comparison of the characteristics of patients with invasive infections and noninvasive infections caused by Trichosporon asahii. (2nd September 2020)

• Record Type: Journal Article
• Authors: Kim, Jinyeong; Kim, Min Jae; Chong, Yong Pil; Kim, Sung-Han; Choi, Sang-Ho; Lee, Sang-Oh; Woo, Jun Hee; Kim, Yang Soo; Jung, Jiwon
• Is Part Of: Medical mycology. Volume 59:Number 3(2021)
• Page Start: 296
• Page End: 300
• Publication Date: 2020-09-02
• Subjects: Trichosporon asahii -- Invasive -- Infection -- Fungemia -- Mortality; Medical mycology -- Periodicals; Veterinary mycology -- Periodicals; Mycology -- Periodicals; Mycoses -- Periodicals; Pathogenic fungi -- Periodicals; 616.969005
• DOI: 10.1093/mmy/myaa076
• Languages: English
• ISSNs: 1369-3786

Abstract

Abstract: We performed retrospective study to identify the characteristics of invasive Trichosporon asahii infection. A total of 102 patients with T. asahii were identified including 18 (18%) with invasive infection. Invasive infection was associated with indwelling central venous catheter (94% vs 54%, P = .001), prior antifungal agent use (50% vs 18%, P = .01), hematologic malignancy (33% vs 7%, P = .006), and end-stage renal disease (28% vs 7%, P = .02). Patients with invasive infections had higher in-hospital mortality than patients with noninvasive infections (61% vs 27%, P = .006). Those with the above risk factors should be monitored for the development of invasive T. asahii infection. Lay summary: Patients with indwelling central venous catheter, prior antifungal agent use, hematologic malignancy, and end-stage renal disease were associated with invasive Trichosporon asahii infection. Patients with invasive infections had higher in-hospital mortality than patients without invasive infection.