Calcified extra-axial cavernous malformation arising from lower cranial nerves: A case report and literature review. Issue 5 (5th February 2021)

• Record Type: Journal Article
• Authors: Ke, Daibo; Deng, Xueyun; Li, Xiang; Li, Jiuhong; Hui, Xuhui
• Other Names: Saranathan. Maya section editor.
• Is Part Of: Medicine. Volume 100:Issue 5(2021)
• Publication Date: 2021-02-05
• Subjects: calcification -- cavernous malformations -- cranial nerves; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000024566
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Extra-axial cavernous malformations (ECMs) arising from cranial nerves (CNs) are rare. Complete "en bloc" lesion resection and hemosiderin-stained tissue preservation remain the standard treatment, while a different strategy may be needed when the lesion is highly calcified . We report the 3rd calcified ECM-CN and review the clinical features and surgical strategy for this rare condition considering previous literature. Patient concerns: We present a 52-year-old woman with a calcified lesion located in the right lower 1/3 of the cerebellopontine angle. Diagnosis: The diagnosis was calcified ECM-CNs according to the pathological and radiological features. Interventions: A posterior midline craniotomy was performed, and piecemeal resection of the lesion was carried out. Subtotal resection of the lesion was achieved with a small piece left in situ. Outcomes: No symptom or lesion-related recurrence was found during 28 months of follow-up. Lessons: Calcified ECM-CNs are unique cavernous malformations arising from CNs. Piecemeal resection and subtotal or near-total excision are 2 major aspects that differ from the surgical strategy for general ECM-CNs.