Gut Microbiome and Nonalcoholic Fatty Liver Disease (NAFLD): Implications for Nursing Care of Individuals Living With Chronic Metabolic Diseases. (January 2021)

• Record Type: Journal Article
• Authors: Liang, Yinji; Zhou, Shuang; Chen, Xinhe; Yu, Lebing; Zhang, Dongling; Lin, Chenli
• Is Part Of: Gastroenterology nursing. Volume 44:Number 1(2021)
• Publication Date: 2021-01
• Subjects: Digestive organs -- Diseases -- Nursing -- Periodicals; 616.330231
• DOI: 10.1097/SGA.0000000000000545
• Languages: English
• ISSNs: 1042-895X

Abstract

Abstract : At present, the incidence of nonalcoholic fatty liver disease (NAFLD) in adults is increasing year by year and at a younger age. Evidence-based healthcare has confirmed that NAFLD is closely related to obesity, cardiovascular disease, type 2 diabetes, metabolic syndrome, and other chronic metabolic diseases. Despite the growing prevalence of NAFLD, little is known about symptoms for patients at risk of NAFLD progression, thus preventing healthcare providers from intervening at an early stage. In addition, these symptoms usually cause problems for patients to cope with other chronic metabolic diseases. Symptoms may have a biological basis; especially as the changes of gut microbes may affect the symptoms of metabolic diseases. This article aims to describe the new role of gut microbes in the development of NAFLD, focusing on the potential relationship between gut microbes and symptoms of NAFLD, as well as the mechanism of action of the "gut–liver–brain" axis. This information can be useful in developing precise nursing interventions for NAFLD patients, restoring the "health" of gut microbes, and alleviating the symptom burden of chronic metabolic disease in NAFLD.