Systemic Therapy for Head and Neck Skin Cancers. (June 2021)

• Record Type: Journal Article
• Authors: Knackstedt, Rebecca; Taub, Peter; Rogers, Gary; Gastman, Brian
• Is Part Of: FACE. Volume 2:Number 2(2021)
• Page Start: 121
• Page End: 130
• Publication Date: 2021-06
• Subjects: skin cancer -- systemic therapy -- melanoma; 617.5
• DOI: 10.1177/27325016211013880
• Languages: English
• ISSNs: 2732-5016

Abstract

The mainstay of curative therapy for head and neck skin cancers relies upon surgery and/or radiation therapy. However, for some aggressive, non-resectable or recurrent tumors, systemic therapy is necessary. Recent emerging classes of drugs have shown to improve survival for high-risk, recurrent, and unresectable variants of these tumors. The goal of this paper is to review options for systemic therapies for head and neck skin cancers including melanoma, non-melanoma skin cancers and other rare and non-malignant tumors.