ACG Clinical Guideline: Primary Sclerosing Cholangitis. (May 2015)

• Record Type: Journal Article
• Authors: Lindor, Keith D; Kowdley, Kris V; Harrison, Edwyn M
• Is Part Of: American journal of gastroenterology. Volume 110:Number 5(2015)
• Publication Date: 2015-05
• Subjects: Stomach -- Diseases -- Periodicals; Intestines -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Gastrointestinal Diseases -- Periodicals; Electronic journals; Periodicals; 616.33
• DOI: 10.1038/ajg.2015.112
• Languages: English
• ISSNs: 0002-9270

Abstract

Abstract : N/A: Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat‐soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.