Lipase Elevation in Patients With COVID-19. (August 2020)

• Record Type: Journal Article
• Authors: McNabb-Baltar, Julia; Jin, David X.; Grover, Amit S.; Redd, Walker D.; Zhou, Joyce C.; Hathorn, Kelly E.; McCarty, Thomas R.; Bazarbashi, Ahmad N.; Shen, Lin; Chan, Walter W.
• Is Part Of: American journal of gastroenterology. Volume 115:Number 8(2020)
• Publication Date: 2020-08
• Subjects: Stomach -- Diseases -- Periodicals; Intestines -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Gastrointestinal Diseases -- Periodicals; Electronic journals; Periodicals; 616.33
• DOI: 10.14309/ajg.0000000000000732
• Languages: English
• ISSNs: 0002-9270

Abstract

Abstract : INTRODUCTION: Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19. METHODS: A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19. RESULTS: Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms. DISCUSSION: Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.