Influenza-C-virion-associated RNA-dependent RNA-polymerase activity. Issue 8 (August 1984)

• Record Type: Journal Article
• Authors: Nagele, Arno; Meier-Ewert, Herbert
• Is Part Of: Bioscience reports. Volume 4:Issue 8(1984)
• Page Start: 703
• Page End: 706
• Publication Date: 1984-08
• Subjects: Molecular biology -- Periodicals; Cytology -- Periodicals; 572.8
• DOI: 10.1007/BF01121024
• Languages: English
• ISSNs: 0144-8463

Abstract

Abstract : The addition of detergent-solubilized influenza C virus to a reaction mixture containing ATP, CTP, GTP, [ 3 H]UTP, and Mg 2+ leads to the synthesis of an acid-insoluble, radioactive product) which is ribonucJease-sensitive. The dinucleoside monophosphate ApG clearly enhances the reaction rate, a fact which indicates that influenza C viruses follow the same strategy of transcription as influenza A and B viruses, the other members of the orthomyxovirus family.