Proteolytic cascade in the amyloidogenesis of Alzheimer's disease. (1st February 2004)
- Record Type:
- Journal Article
- Title:
- Proteolytic cascade in the amyloidogenesis of Alzheimer's disease. (1st February 2004)
- Main Title:
- Proteolytic cascade in the amyloidogenesis of Alzheimer's disease
- Authors:
- Sidera, C.
Parsons, R.
Austen, B. - Abstract:
- Abstract : β-Amyloid, a neurotoxic peptide deposited in the brains of Alzheimer's disease patients, is released by a series of membrane-limited proteolytic events. β-Secretase activity is enhanced by cellular targeting into intracellular cholesterol-rich microdomains, which are dispersed by statins.
- Is Part Of:
- Biochemical Society transactions. Volume 32:Number 1(2004)
- Journal:
- Biochemical Society transactions
- Issue:
- Volume 32:Number 1(2004)
- Issue Display:
- Volume 32, Issue 1 (2004)
- Year:
- 2004
- Volume:
- 32
- Issue:
- 1
- Issue Sort Value:
- 2004-0032-0001-0000
- Page Start:
- 33
- Page End:
- 36
- Publication Date:
- 2004-02-01
- Subjects:
- Alzheimer's disease -- amyloidogenesis -- cholesterol -- glycosylation -- lovastatin -- proteolysis -- β-secretase
Biochemistry -- Congresses
572 - Journal URLs:
- https://portlandpress.com/biochemsoctrans ↗
- DOI:
- 10.1042/bst0320033 ↗
- Languages:
- English
- ISSNs:
- 0300-5127
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 15924.xml