Quantification of the effects of melittin on liposome structure. (26th October 2005)

• Record Type: Journal Article
• Authors: Popplewell, J.; Freeman, N.; Carrington, S.; Ronan, G.; McDonnell, C.; Ford, R.C.
• Is Part Of: Biochemical Society transactions. Volume 33:Number 5(2005)
• Page Start: 931
• Page End: 933
• Publication Date: 2005-10-26
• Subjects: dual-polarization interferometry -- lipid–peptide interaction -- liposome structure -- melittin -- membrane mimic; Biochemistry -- Congresses; 572
• DOI: 10.1042/BST0330931
• Languages: English
• ISSNs: 0300-5127

Abstract

Abstract : An optical technique, dual-polarization interferometry, has been used to examine lipid structures at the solid/liquid interface. Changes in the lipid structures, in real time, were examined as a consequence of challenging them with a peptide (melittin) that is known to induce liposome rupture. This work suggests that it should be possible to obtain a better understanding of the detail of the melittin rupture process.