Sequence of ionophore conformational changes induced by a simulated membrane/water interface. Issue 8 (August 1984)

• Record Type: Journal Article
• Authors: Brasseur, Robert; Deleers, Michel; Ruysschaert, Jean-Marie
• Is Part Of: Bioscience reports. Volume 4:Issue 8(1984)
• Page Start: 651
• Page End: 658
• Publication Date: 1984-08
• Subjects: Molecular biology -- Periodicals; Cytology -- Periodicals; 572.8
• DOI: 10.1007/BF01121018
• Languages: English
• ISSNs: 0144-8463

Abstract

Abstract : We demonstrate how the progressive passage through an interface simulated by a linear increase in dielectric constant may mediate a reversible transconformation of Na + /X337A (lasalocid A) from a cyclic to an extended structure, During the passage through the interface, the complex adopts progressively a more extended conformation favorable to the Na + complexation or decomplexation at the interface.