B-cell development and antigen receptor signalling. (August 2002)
- Record Type:
- Journal Article
- Title:
- B-cell development and antigen receptor signalling. (August 2002)
- Main Title:
- B-cell development and antigen receptor signalling
- Authors:
- Turner, M.
- Abstract:
- Abstract : B-cell development and function requires the products of the Vav family of genes. Vav proteins act as key components of the antigen receptor signal transduction machinery by integration of signals that control the cell cycle, differentiation and apoptosis. At the molecular level, Vav proteins regulate small-molecular-mass GTPases, phosphoinositide 3-kinase, TEC family tyrosine kinases and intracellular calcium flux.
- Is Part Of:
- Biochemical Society transactions. Volume 30:Number 4(2002)
- Journal:
- Biochemical Society transactions
- Issue:
- Volume 30:Number 4(2002)
- Issue Display:
- Volume 30, Issue 4 (2002)
- Year:
- 2002
- Volume:
- 30
- Issue:
- 4
- Issue Sort Value:
- 2002-0030-0004-0000
- Page Start:
- 812
- Page End:
- 815
- Publication Date:
- 2002-08
- Subjects:
- calcium -- knockout mice -- lymphocyte activation
BCR, B-cell receptor -- Btk, Bruton's tyrosine kinase -- PI 3-kinase, phosphoinositide 3-kinase -- PLC-γ2, phospholipase Cγ2 -- T-D, thymus-dependent -- TI-2, type-2 thymusindependent
Biochemistry -- Congresses
572 - Journal URLs:
- https://portlandpress.com/biochemsoctrans ↗
- DOI:
- 10.1042/bst0300812 ↗
- Languages:
- English
- ISSNs:
- 0300-5127
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 15889.xml