Concise synthesis of chiral pyrazolo[4, 3‐f] [1, 4]oxazepines and pyrazolo[4, 3‐f] [1, 4]thiazepines bearing pyrazole unit. (10th December 2020)
- Record Type:
- Journal Article
- Title:
- Concise synthesis of chiral pyrazolo[4, 3‐f] [1, 4]oxazepines and pyrazolo[4, 3‐f] [1, 4]thiazepines bearing pyrazole unit. (10th December 2020)
- Main Title:
- Concise synthesis of chiral pyrazolo[4, 3‐f] [1, 4]oxazepines and pyrazolo[4, 3‐f] [1, 4]thiazepines bearing pyrazole unit
- Authors:
- Pitchai, Manivel
Ulaganathan, Sankar
Venkateshappa, Suresh Shagathur
Akunuri, Arun
Rampulla, Richard
Mathur, Arvind
Gupta, Anuradha - Abstract:
- Abstract: An efficient synthesis of pyrazolo [1, 4]‐oxazepines and [1, 4]‐thiazepines bearing a variety of alkyl and aryl groups with a chiral center has been developed. The synthesis started with readily available 5‐chloro‐pyrazole‐4‐carbaldehyde and chiral amino alcohols. The key step involves intramolecular imine formation. These classes of compounds are potentially useful as templates for drug discovery. Abstract :
- Is Part Of:
- Journal of heterocyclic chemistry. Volume 58:Number 2(2021)
- Journal:
- Journal of heterocyclic chemistry
- Issue:
- Volume 58:Number 2(2021)
- Issue Display:
- Volume 58, Issue 2 (2021)
- Year:
- 2021
- Volume:
- 58
- Issue:
- 2
- Issue Sort Value:
- 2021-0058-0002-0000
- Page Start:
- 558
- Page End:
- 568
- Publication Date:
- 2020-12-10
- Subjects:
- Heterocyclic compounds -- Periodicals
547.59 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/jhet.4195 ↗
- Languages:
- English
- ISSNs:
- 0022-152X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4998.200000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 15887.xml