Emotional traumatic experiences significantly contribute to identify a maltreated ecophenotype sub‐group in eating disorders: Experimental evidence. (30th December 2020)

• Record Type: Journal Article
• Authors: Monteleone, Alessio Maria; Cascino, Giammarco; Ruzzi, Valeria; Pellegrino, Francesca; Patriciello, Giuseppina; Barone, Eugenia; Carfagno, Marco; Monteleone, Palmiero; Maj, Mario
• Is Part Of: European eating disorders review. Volume 29:Number 2(2021)
• Page Start: 269
• Page End: 280
• Publication Date: 2020-12-30
• Subjects: childhood trauma -- eating disorders -- emotional trauma -- maltreated ecophenotype -- Trier Social Stress Test; Eating disorders -- Periodicals; 616.8526
• DOI: 10.1002/erv.2818
• Languages: English
• ISSNs: 1072-4133

Abstract

Abstract: Objective: Eating disorders (EDs) are associated with a high prevalence of childhood maltreatment (CM). We aimed to experimentally assess if people with EDs and history of CM show altered biological, emotional and behavioural responses to the Trier Social Stress Test (TSST). Methods: According to Childhood Trauma Questionnaire cut‐off scores, 29 participants (14 with anorexia nervosa [AN] and 15 with bulimia nervosa [BN]) were classified as maltreated (Mal) ED participants while 19 participants (11 with AN and eight with BN) without CM were identified as no maltreated (noMal) ED participants. Cortisol, anxiety and hunger responses to TSST and post‐stress body dissatisfaction were measured. Results: Mal ED people showed heightened emotional reactivity, lower levels of hunger and more severe post‐stress body dissatisfaction in comparison with noMal ones. Higher cortisol production was observed in people with AN, regardless of CM history, and in those with BN and emotional CM. Emotional trauma was the main CM type contributing to the experimental differences observed in Mal ED people. Conclusions: This is the first study providing experimental and multi‐level support to the maltreated ecophenoptype hypothesis in people with EDs. These findings may promote new insights into the biological bases of EDs and provide novel therapeutic implications. Highlights: Childhood maltreatment affects psychological and biological responses to acute psychosocial stress in people with eating disorders (EDs) Emotional trauma is the main childhood maltreatment type contributing to the observed experimental differences Experimental and multi‐level data support the identification of a maltreated ecophenoptype in people with EDs