Optical coherence tomography: From technology to applications in ophthalmology. Issue 1 (20th November 2020)

• Record Type: Journal Article
• Authors: Everett, Matthew; Magazzeni, Stephanie; Schmoll, Tilman; Kempe, Michael
• Is Part Of: Translational biophotonics. Volume 3:Issue 1(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-11-20
• Subjects: angiography -- ophthalmology -- optical coherence tomography -- retina -- standard of care; Imaging systems in medicine -- Periodicals; Biosensors -- Optical properties -- Periodicals; Photonics -- Periodicals; Imaging systems in medicine; Photonics; Optics and Photonics; Translational Medical Research; Periodicals; Periodical; 621.365
• DOI: 10.1002/tbio.202000012
• Languages: English
• ISSNs: 2627-1850

Abstract

Abstract: The relatively fast translation of optical coherence tomography (OCT) from an optical measurement technology to a standard of care in ophthalmology was driven by its ability to address clear unmet diagnostic needs. OCT's further technological developments have expanded its clinical use by extending the imaging range (wider, deeper) and the imaging contrast (from morphology to blood flow). The translation of technical advances into clinical value is an ongoing process involving both the potential substitution of established diagnostics (such as fundus angiography) and the identification of novel feature‐disease correlations. This review looks into the development, the status and the prospects of OCT with regard to translation to clinical routine in ophthalmology. Abstract : This article reviews the development history and current status of optical coherence tomography (OCT) as a standard of care in ophthalmology. OCT's unique ability to visualize the microstructure of the retinal layers and anterior segment of the eye addressed unmet diagnostic needs, thus driving market acceptance. Ongoing technology developments continue to be translated into clinical routine, further expanding applications, for example, imaging of physiological function and additional eye structures. Image shows widefield swept source OCT angiography image of the right eye of a 56‐year‐old male patient with branch retinal vein occlusion with courtesy of Dr Ali Erginay, Lariboisière Hospital, Paris, France.