Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study. Issue 3 (10th December 2020)
- Record Type:
- Journal Article
- Title:
- Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study. Issue 3 (10th December 2020)
- Main Title:
- Hepatitis B infection and risk factors among pregnant women and their male partners in the Baby Shower Programme in Nigeria: a cross‐sectional study
- Authors:
- Talla, Carol
Itanyi, Ijeoma Uchenna
Tsuyuki, Kiyomi
Stadnick, Nicole
Ogidi, Amaka Grace
Olakunde, Babayemi Oluwaseun
Patel, Dina
Oko, John Okpanachi
Aarons, Gregory
Onoka, Chima Ariel
Ezeanolue, Echezona Edozie - Abstract:
- Abstract: Objectives: To determine the population prevalence and determinants of hepatitis B (Hep B) status, and status discordance, among pregnant women and their male partners in Nigeria. Methods: Cross‐sectional study assessing the seroprevalence of Hep B virus in a cohort of 16 920 pregnant women and their male partners in northcentral Nigeria. Rapid HBsAg antibody test was used for Hep B diagnosis. Demographic, socio‐economic and behavioural information was collected through interviewer‐administered questionnaires and evaluated as determinants of Hep B status and couple status discordance using logistic regression. Results: Of 16 920 participants who had a Hep B test result, 6750 couples and 1316 discordant couples were identified. The prevalence of Hep B among all participants was 10.9%, with lower prevalence among pregnant women (10.2%) than their male partners (11.9%), P < 0.001. The prevalence of Hep B sero‐discordance among couples was 19.5% (1316/6750). Younger age, prior Hep B testing and a prior positive Hep B test increased the odds of Hep B infection while being a woman decreased the odds of Hep B among all participants, and among couples. Furthermore, polygamy (adjusted odds ratio [AOR]: 1.49, 95% confidence interval [CI]: 1.19–1.87), prior Hep B testing (AOR: 2.38, 95% CI: 1.14–4.97) and a prior positive Hep B test result were significant determinants of status discordance among the participating couples. Conclusion: The prevalence of Hep B among pregnantAbstract: Objectives: To determine the population prevalence and determinants of hepatitis B (Hep B) status, and status discordance, among pregnant women and their male partners in Nigeria. Methods: Cross‐sectional study assessing the seroprevalence of Hep B virus in a cohort of 16 920 pregnant women and their male partners in northcentral Nigeria. Rapid HBsAg antibody test was used for Hep B diagnosis. Demographic, socio‐economic and behavioural information was collected through interviewer‐administered questionnaires and evaluated as determinants of Hep B status and couple status discordance using logistic regression. Results: Of 16 920 participants who had a Hep B test result, 6750 couples and 1316 discordant couples were identified. The prevalence of Hep B among all participants was 10.9%, with lower prevalence among pregnant women (10.2%) than their male partners (11.9%), P < 0.001. The prevalence of Hep B sero‐discordance among couples was 19.5% (1316/6750). Younger age, prior Hep B testing and a prior positive Hep B test increased the odds of Hep B infection while being a woman decreased the odds of Hep B among all participants, and among couples. Furthermore, polygamy (adjusted odds ratio [AOR]: 1.49, 95% confidence interval [CI]: 1.19–1.87), prior Hep B testing (AOR: 2.38, 95% CI: 1.14–4.97) and a prior positive Hep B test result were significant determinants of status discordance among the participating couples. Conclusion: The prevalence of Hep B among pregnant women and their male partners in northcentral Nigeria is high. A large‐scale intervention is required to reduce Hep B prevalence in this setting. Abstract : Objectifs: Déterminer la prévalence dans la population et les déterminants du statut de l'hépatite B (Hep B) et de la discordance de statut chez les femmes enceintes et leurs partenaires masculins au Nigéria. Méthodes: Etude transversale évaluant la séroprévalence du virus Hep B dans une cohorte de 16.920 femmes enceintes et leurs partenaires masculins dans le centre‐nord du Nigéria. Un test rapide des anticorps anti‐HBsAg a été utilisé pour le diagnostic de l'Hep B. Des informations démographiques, socio‐économiques et comportementales ont été recueillies au moyen de questionnaires administrés par les intervieweurs et évaluées en tant que déterminants du statut Hep B et de la discordance du statut de couple à l'aide de la régression logistique. Résultats: Sur 16.920 participants qui avaient un résultat de dépistage de l'Hep B, 6.750 couples et 1.316 couples discordants ont été identifiés. La prévalence de l'Hep B chez tous les participants était de 10, 9%, avec une prévalence plus faible chez les femmes enceintes (10, 2%) que chez leurs partenaires masculins (11, 9%), p <0, 001. La prévalence de la séro‐discordance de l'Hep B chez les couples était de 19, 5% (1.316/6.750). Un âge plus jeune, un dépistage antérieur de l'Hep B et un test Hep B positif antérieur augmentaient les risques d'infection à l'Hep B alors que le sexe féminin diminuait les risques d'Hep B chez tous les participants et parmi les couples. De plus, la polygamie (rapport de cotes ajusté [AOR]: 1, 49, intervalle de confiance [IC] à 95%: 1, 19‐1, 87), un dépistage antérieur de l'Hep B (AOR: 2, 38 ; IC95%: 1, 14‐4, 97) et un test hépatique B positif antérieur résultat étaient des déterminants significatifs de la discordance de statut parmi les couples participants. Conclusion: La prévalence de l'Hep B chez les femmes enceintes et leurs partenaires masculins dans le centre‐nord du Nigéria est élevée. Une intervention à grande échelle est nécessaire pour réduire la prévalence de l'Hep B dans cette région. … (more)
- Is Part Of:
- Tropical medicine & international health. Volume 26:Issue 3(2021)
- Journal:
- Tropical medicine & international health
- Issue:
- Volume 26:Issue 3(2021)
- Issue Display:
- Volume 26, Issue 3 (2021)
- Year:
- 2021
- Volume:
- 26
- Issue:
- 3
- Issue Sort Value:
- 2021-0026-0003-0000
- Page Start:
- 316
- Page End:
- 326
- Publication Date:
- 2020-12-10
- Subjects:
- Hepatitis B -- prevalence -- pregnant women -- sexual partners -- Nigeria
Tropical medicine -- Periodicals
Public health -- Periodicals
616.988 - Journal URLs:
- http://www.blackwell-synergy.com/member/institutions/issuelist.asp?journal=tmi ↗
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-3156 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1111/tmi.13531 ↗
- Languages:
- English
- ISSNs:
- 1360-2276
- Deposit Type:
- Legaldeposit
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- Available online (eLD content is only available in our Reading Rooms) ↗
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- British Library DSC - 9056.402000
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