Association of attention‐deficit/hyperactivity disorder with diabetes mellitus in US adults. Issue 4 (5th October 2020)

• Record Type: Journal Article
• Authors: Xu, Guifeng; Liu, Buyun; Yang, Wenhan; Snetselaar, Linda G.; Jing, Jin
• Is Part Of: Journal of diabetes. Volume 13:Issue 4(2021)
• Page Start: 299
• Page End: 306
• Publication Date: 2020-10-05
• Subjects: attention‐deficit/hyperactivity disorder -- diabetes -- epidemiology; 注意缺陷/多动症 -- 糖尿病 -- 流行病学; Diabetes -- Periodicals; 618.3646005
• DOI: 10.1111/1753-0407.13107
• Languages: English
• ISSNs: 1753-0393

Abstract

Abstract: Background: Attention‐deficit/hyperactivity disorder (ADHD) is a childhood‐onset neurodevelopmental disorder that usually persists into adulthood. However, limited evidence is available regarding its influence on adult health outcomes beyond neuropsychiatric comorbidities. This study aimed to examine the association of ADHD with diabetes in US adults. Methods: We analyzed data from the National Health Interview Survey (NHIS), a leading health survey of a nationally representative sample in the United States. We included adults aged 20‐79 years who participated in the NHIS 2007 and 2012. Physician‐diagnosed ADHD and diabetes were reported during an in‐person household interview. Logistic regression with survey sampling weights was used to estimate the odds ratio (OR) and 95% confidence interval (CI) of diabetes. Results: This analysis included 52 821 adults (weighted mean age 45.5 years; 48.6% males). Among them, 1642 participants reported a diagnosis of ADHD and 4631 reported a diagnosis of diabetes. In the multivariable analysis adjusting for age, sex, race/ethnicity, education level, family income level, smoking, alcohol drinking, physical activity, and body mass index, the OR of diabetes among adults with ADHD vs those without ADHD was 1.54 (95% CI, 1.16‐2.04). In the stratified analyses, the significant association of ADHD with diabetes remained in most strata, and the associations were not significantly modified by age, sex, race/ethnicity, or obesity status. Conclusions: In a nationally representative sample of US adults, we found a significant association between a history of ADHD diagnosis and diabetes. Abstract : Highlights Attention‐deficit/hyperactivity disorder (ADHD) is associated with neuropsychiatric comorbidities in adults. Limited evidence is available regarding its association with physical health outcomes in adults. In a nationally representative sample of US adults, we found a significant association between a history of ADHD diagnosis and diabetes. The findings extend the knowledge on the relationship between ADHD and diabetes, which highlights the need for further research about the association of neurodevelopmental disorders with their physical health outcomes in adults. 摘要: 背景: 注意缺陷力/多动症(ADHD)是一种儿童期出现并通常持续到成年的一种神经发育障碍。除外神经精神病合并症以外, ADHD对患者长期健康结局影响的研究证据非常有限。本项研究旨在了解美国成人ADHD与糖尿病的关系。 方法: 美国国家健康访谈调查(NHIS)是一项针对美国全国代表性样本的健康调查。我们纳入了2007年和2012参加这项调查的20‐79岁成年人。在面对面的家庭访谈中收集了ADHD和糖尿病的诊断信息。用纳入了调查样本权重的逻辑回归分析来估计糖尿病的优势比(OR)和95%置信区间(CI)。 结果: 这项分析包括52821名成年人(加权平均年龄45.5岁；48.6%为男性)。其中, 有1642名受试者报告了ADHD的诊断, 4631名受试者报告了糖尿病的诊断。在对年龄, 性别, 种族/族裔, 教育程度, 家庭收入水平, 吸烟, 饮酒, 体育锻炼和体重指数进行校正的多变量分析中, 患有ADHD的成年人与未患ADHD的成年人相比, 其糖尿病OR为1.54(95 % CI:1.16‐2.04)。在分层分析中, ADHD与糖尿病之间的显著关联存在于大多数层级中, 并且该关联并未因年龄, 性别, 种族/民族或肥胖状况有明显改变。 结论: 在美国成年人的全国代表性样本中, 我们发现了ADHD的诊断历史与糖尿病之间存在显著关联。