Chemical composition and biological potential of Thymus Willdenowii Boiss. & Reut. essential oil. Issue 5 (4th March 2021)

• Record Type: Journal Article
• Authors: Zeghib, Assia; Calliste, Claude-Alain; Simon, Alain; Charfeddine, Rim; Aouni, Mahjoub; Duroux, Jean-Luc; Kabouche, Ahmed; Kabouche, Zahia
• Is Part Of: Natural product research. Volume 35:Issue 5(2021)
• Page Start: 845
• Page End: 848
• Publication Date: 2021-03-04
• Subjects: Thymus willdenowii Boiss. & Reut. -- essential oil -- cytotoxicity -- antibacterial -- antiproliferative -- antioxidant -- antiviral; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1602830
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: The fresh aerial parts of Thymus willdenowii Boiss. & Reut. (syn. Thymus hirtus Willd.) were hydrodistilled in a Clevenger type apparatus and analyzed by GC and GC-MS. 44 Components were identified representing 97.3%, with 1, 8-cineole (34.62%), camphor (18.55%), α-pinene (9.46%) and camphene (5.38%) as the main components. T. willdenowii essential oil was not cytotoxic (CC50 = 97.65 µg/mL) towards Vero non-tumoural cells, exhibiting good antibacterial and antiproliferative (30.8 ± 3.1% inhibition) potentials against four tested pathogenic bacteria and Human colorectal cell line HT-29, respectively. The essential oil did not show a DPPH radical scavenging activity, by Electron Spin Resonance spectroscopy (ESR), and it lacks antiviral effect towards coxsackievirus B3. Graphical Abstract: