Phytochemical analysis and evaluation of antioxidant and antimycobacterial activity of Colletia paradoxa from Brazil. Issue 5 (4th March 2021)

• Record Type: Journal Article
• Authors: Bastos Záchia, Nelci Rolim; Piana, Mariana; dos Santos Siqueira, Fallon; da Silva Jesus, Roberta; Athayde, Margareth Linde; Essi, Liliana; de Campos, Marli Matiko Anraku
• Is Part Of: Natural product research. Volume 35:Issue 5(2021)
• Page Start: 802
• Page End: 806
• Publication Date: 2021-03-04
• Subjects: DPPH -- flavonoids -- HPLC -- morphotypes -- rhamnaceae -- biological activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1598987
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability. Our objective is to investigate the phytochemical components, antioxidant capacity and antimycobacterial activity of different morphotypes of C. paradoxa in different environments. For this, the crude extract of the leaves and branches of the individuals sampled was used. The elimination capacity of the free radicals was determined by the DPPH method, the antimycobacterial activity by the broth microdilution method and the phenolic content by the spectrophotometric method using the Folin-Ciocalteu reagent and by HPLC. The extracts of C. paradoxa and its morphotypes showed significant amounts of phenolic compounds, including quercetin, quercitrin and rutin, besides considerable antioxidant and antimycobacterial activity No connection was detected between the phytochemical composition and different morphotypes of C. paradoxa . Graphical Abstract: