Selective release of a potent anticancer agent from a supramolecular hydrogel using green light. Issue 15 (24th February 2021)

• Record Type: Journal Article
• Authors: Karcher, Johannes; Kirchner, Susanne; Leistner, Anna-Lena; Hald, Christian; Geng, Philipp; Bantle, Tobias; Gödtel, Peter; Pfeifer, Juliana; Pianowski, Zbigniew L.
• Is Part Of: RSC advances. Volume 11:Issue 15(2021)
• Page Start: 8546
• Page End: 8551
• Publication Date: 2021-02-24
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d0ra08893e
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Selective green-light triggered release of an anticancer agent under physiological conditions from a supramolecular hydrogel. Abstract : Light-triggered drug release from hydrogels is a promising method to improve efficiency of antitumor treatment, as an alternative to existing photodynamic therapies. Here we report a photochromic supramolecular low-MW hydrogel that can quickly and selectively release a physically encapsulated potent anticancer agent upon green light irradiation under physiological conditions.