A formal [3 + 3] cycloaddition of allenyl imide and activated ketones for the synthesis of tetrasubstituted 2-pyrones. Issue 15 (26th February 2021)

• Record Type: Journal Article
• Authors: Wang, Yu-Hao; Zhang, De-Hua; Cao, Ze-Hun; Li, Wang-Lai; Huang, Yi-Yong
• Is Part Of: RSC advances. Volume 11:Issue 15(2021)
• Page Start: 8867
• Page End: 8870
• Publication Date: 2021-02-26
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d0ra10686k
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : CsOH·H2 O-catalyzed formal [3 + 3] cycloadditions of allenyl imide with β-ketoesters, 1, 3-diketones or β-ketonitriles for the synthesis of tetrasubstituted 2-pyrone derivatives were reported. Abstract : CsOH·H2 O-catalyzed formal [3 + 3] cycloadditions of allenyl imide with β-ketoesters, 1, 3-diketones or β-ketonitriles for the synthesis of tetrasubstituted 2-pyrone derivatives have been demonstrated. The allenyl imide was utilized as a C3-synthon, and a ketenyl intermediate was proposed via the process of 1, 4-addition of carbon anion to allene followed by elimination of the 2-oxazolidinyl group.