Efficient photorelease of carbon monoxide from a luminescent tricarbonyl rhenium(i) complex incorporating pyridyl-1, 2, 4-triazole and phosphine ligands. Issue 4 (6th January 2021)

• Record Type: Journal Article
• Authors: Hernández Mejías, Ángel D.; Poirot, Alexandre; Rmili, Meriem; Leygue, Nadine; Wolff, Mariusz; Saffon-Merceron, Nathalie; Benoist, Eric; Fery-Forgues, Suzanne
• Is Part Of: Dalton transactions. Volume 50:Issue 4(2020)
• Page Start: 1313
• Page End: 1323
• Publication Date: 2021-01-06
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/d0dt03577g
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : In this new Re(i ) PhotoCORM, the efficient photoproduction of carbon monoxide is visualized through a strong colour change of the emitted phosphorescence. Abstract : Precise control over the production of carbon monoxide (CO) is essential to exploit the therapeutic potential of this molecule. The development of photoactive CO-releasing molecules (PhotoCORMs) is therefore a promising route for future clinical applications. Herein, a tricarbonyl-rhenium(i ) complex (1-TPP ), which incorporates a phosphine moiety as ancilliary ligand for boosting the photochemical reactivity, and a pyridyltriazole bidentate ligand with appended 2-phenylbenzoxazole moiety for the purpose of photoluminescence, was synthesized and characterized from a chemical and crystallographic point of view. Upon irradiation in the near-UV range, complex 1-TPP underwent fast photoreaction, which was monitored through changes of the UV-vis absorption and phosphorescence spectra. The photoproducts ( i.e. the dicarbonyl solvento complex 2 and one CO molecule) were identified using FTIR, 1 H NMR and HRMS. The results were interpreted on the basis of DFT/TD-DFT calculations. The effective photochemical release of CO associated with clear optical variations (the emitted light passed from green to orange-red) could make 1-TPP the prototype of new photochemically-active agents, potentially useful for integration in photoCORM materials.