A pyrone remodeling strategy to access diverse heterocycles: application to the synthesis of fascaplysin natural products. Issue 4 (11th December 2020)
- Record Type:
- Journal Article
- Title:
- A pyrone remodeling strategy to access diverse heterocycles: application to the synthesis of fascaplysin natural products. Issue 4 (11th December 2020)
- Main Title:
- A pyrone remodeling strategy to access diverse heterocycles: application to the synthesis of fascaplysin natural products
- Authors:
- Palani, Vignesh
Perea, Melecio A.
Gardner, Kristen E.
Sarpong, Richmond - Abstract:
- Abstract : The synthesis of diverse N -fused heterocycles, including the pyrido[1, 2- a ]indole scaffold, using an efficient pyrone remodeling strategy is described. Abstract : The synthesis of diverse N -fused heterocycles, including the pyrido[1, 2- a ]indole scaffold, using an efficient pyrone remodeling strategy is described. The pyrido[1, 2- a ]indole core was demonstrated to be a versatile scaffold that can be site-selectively functionalized. The utility of this novel annulation strategy was showcased in a concise formal synthesis of three fascaplysin congeners.
- Is Part Of:
- Chemical science. Volume 12:Issue 4(2021)
- Journal:
- Chemical science
- Issue:
- Volume 12:Issue 4(2021)
- Issue Display:
- Volume 12, Issue 4 (2021)
- Year:
- 2021
- Volume:
- 12
- Issue:
- 4
- Issue Sort Value:
- 2021-0012-0004-0000
- Page Start:
- 1528
- Page End:
- 1534
- Publication Date:
- 2020-12-11
- Subjects:
- Chemistry -- Periodicals
540.5 - Journal URLs:
- http://pubs.rsc.org/en/Journals/JournalIssues/SC ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d0sc06317g ↗
- Languages:
- English
- ISSNs:
- 2041-6520
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3151.490000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 15840.xml