Considering the Supraorganism: Harnessing the Gut Microbiome for Cancer Prevention, Detection, and Treatment. (July 2019)

• Record Type: Journal Article
• Authors: Hollister, Emily B.
• Is Part Of: American journal of gastroenterology. Volume 114:Number 7(2019)
• Publication Date: 2019-07
• Subjects: Stomach -- Diseases -- Periodicals; Intestines -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Gastrointestinal Diseases -- Periodicals; Electronic journals; Periodicals; 616.33
• DOI: 10.14309/ajg.0000000000000180
• Languages: English
• ISSNs: 0002-9270

Abstract

Abstract : Abstract: Although causal relationships between specific microbes and cancer are well recognized, a growing body of evidence suggests that the broader community of gut microbes may influence cancer risk, provide diagnostic insight, shape clinical course, and impact treatment success in the gastrointestinal tract and beyond. In this issue, Murphy et al. reviewed evidence for the role of the microbiome in clinical oncology. Given that the gut microbiome may be modified by treatments ranging from diet and live biotherapeutics to microbial transplantation, microbiome-directed therapies hold tremendous promise for personalized therapies and improved treatment outcomes.