Radioprotective Activity and Synthesis of Siladithioacetals and Germadithioacetals Derived from N-substituted Naphthylethylimidazoline. Issue 4 (2001)

• Record Type: Journal Article
• Authors: Célariès Célariès, Benoît Benoît; Rima Rima, Ghassoub Ghassoub; Court Court, Louis Louis; Lion Lion, Claude Claude; Laval Laval, Jean-Denis Jean-Denis
• Is Part Of: Metal-based drugs. Volume 8:Issue 4(2001)
• Page Start: 199
• Page End: 210
• Publication Date: 2001
• Subjects: Metals -- Therapeutic use -- Periodicals; Pharmaceutical chemistry -- Periodicals; Drugs -- Periodicals; Drugs; Metals -- Therapeutic use; Pharmaceutical chemistry; Chemistry, Pharmaceutical -- Periodicals; Metals -- therapeutic use -- Periodicals; Pharmaceutical Preparations -- Periodicals; Periodicals; Electronic journals; 615.23
• DOI: 10.1155/MBD.2001.199
• Languages: English
• ISSNs: 0793-0291

Abstract

Abstract : A number of organosilicon and organogermanium derivatives and some related compounds including the N -substituted. 2-[1-naphthylmethyl]-2-imidazoline and 2-[1-(1-naphthyl)ethyl]-2-imidazoline have been prepared and the toxicity of some compounds have been determined in mice. In this paper we report the synthesis and the evaluation of the pharmacological activity of new organosilicon and organogermanium, compounds such as sila- and germadithioacetals derived from N -substituted naphthylimidazolne.