Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis. (2006)

• Record Type: Journal Article
• Authors: Hellwig, Kerstin; Lukas, Carsten; Brune, Niels; Hoffmann, Volker; Schimrigk, Sebastian; Przuntek, Horst; Müller, Thomas
• Other Names: Siegel George Academic Editor.
• Is Part Of: TheScientificWorldjournal. Volume 6(2006)
• Page Start: 460
• Page End: 465
• Publication Date: 2006
• Subjects: relapsing remitting multiple sclerosis -- triamcinolone acetonide -- intrathecal -- dysesthesia -- therapy; Science -- Periodicals; Technology -- Periodicals; Medicine -- Periodicals; 505
• DOI: 10.1100/tsw.2006.86
• Languages: English
• ISSNs: 2356-6140

Abstract

Abstract : We describe four patients with relapsing remitting multiple sclerosis (RRMS) who experienced a relapse with acute onset of painful sensations. Pain sensations disappeared in two of them and markedly reduced in the other ones after repeat application of intrathecal triamcinolone acetonide (TCA) following a prior unsuccessful treatment with intravenous steroids. TCA administration was well tolerated and no serious side effects occurred. Repeated intrathecal TCA injection may provide a substantial benefit in RRMS patients with acute onset of pain due to an inflammatory lesion within the spinal cord.