Craniofacial and occlusal features of children with Noonan syndrome. Issue 3 (13th January 2021)

• Record Type: Journal Article
• Authors: Bagattoni, Simone; Costi, Tommaso; D'Alessandro, Giovanni; Toni, Sara; Gatto, Maria Rosaria; Piana, Gabriela
• Is Part Of: American journal of medical genetics. Volume 185:Issue 3(2021)
• Page Start: 820
• Page End: 826
• Publication Date: 2021-01-13
• Subjects: Noonan syndrome -- occlusion -- oral health; Medical genetics -- Periodicals; 616.14205
• DOI: 10.1002/ajmg.a.62046
• Languages: English
• ISSNs: 1552-4825

Abstract

Abstract: Craniofacial features of 12 children with Noonan syndrome (NS) were compared with age and gender matched healthy children. Dental history, panoramic radiograph, dental casts, and cephalometric measurements were assessed. The palatal height was significantly increased in the study group compared with the control group ( p = .009; paired t ‐test). The palatal width was significantly reduced in the study group compared with the control group ( p = .006; paired t ‐test). The mean SNB was reduced in the study group compared with the control group ( p = .02; paired t ‐test) and the ANB increased ( p = .009; paired t ‐test). The mean Sum (NSAr + SArGo + ArgoMe) angle and SN‐GoMe were increased in the study group compared with the control group (respectively, p = .015 and p = .002; paired t ‐test). The cephalometric analysis assessed a retruded position of the mandible, skeletal class II characteristics, and a vertical growth pattern. The mandibular hyperdivergency was associated to a positive overbite.