Design and engineering of magneto-responsive devices for cancer theranostics: Nano to macro perspective. (February 2021)

• Record Type: Journal Article
• Authors: Soares, Paula I.P.; Romão, Joana; Matos, Ricardo; Silva, Jorge Carvalho; Borges, João Paulo
• Is Part Of: Progress in materials science. Volume 116(2021)
• Publication Date: 2021-02
• Subjects: 3D printing -- Additive manufacturing -- Cancer theranostics -- Electrospinning -- Magnetic nanostructures -- Magneto-responsive device; 0 to 4D zero- to four-dimensional -- ABS acrylonitrile butadiene styrene -- AM additive manufacturing -- ASTM american society for testing and materials -- BEMA bisphenol A ethoxylate dimethacrylate -- BP benzophenone -- CAD computer-aided design -- CT computed tomography -- DLP digital light processing -- DMD digital micro-mirror device -- DS diclofenac sodium -- EGDMA ethylene glycol dimethacrylate -- EMA european medicines agency, EPR, enhanced permeation effect -- FDA food and drug administration -- FDM fused deposition modeling -- GEL gelatin -- GO graphene oxide -- HA hydroxyapatite -- HEMA 2-hydroxy-ethyl-methacrylate -- HMAAm N-hydroxymethyl acrylamide -- ISO international organization for standardization -- LDH layered double hydroxide -- LPSR localized plasmon surface resonance -- MBA N, N-methylene bisacrylamide -- MBG mesoporous bioactive glass -- µCLIP micro-continuous liquid interface production -- MOF metal-organic frameworks -- M-PSL magnetic field-assisted projection stereolithography -- MRI magnetic resonance image -- MWCNT multiwalled carbon nanotubes -- NIPAAm N-isopropyl acrylamide -- NIR near-infrared -- NMR nuclear magnetic resonance -- NPs nanoparticles -- p(MMA-co-DMA) poly (methyl methacrylate-co-dopamine methacrylamide) -- PAA poly (acrylic acid) -- PAAm polyacrylamide -- PAT photoacoustic tomography -- PBS phosphate buffer solution -- PCL polycaprolactone -- PDMS polydimethylsiloxane -- PEG poly (ethylene glycol) -- PEGDA poly (ethylene glycol) diacrylate -- PEI poly (ethylenimine) -- PEO poly (ethylene oxide) -- PET positron emission tomography -- PLA poly (lactic acid) -- PLGA poly (lactic-co-glycolic acid) -- PVA poly (vinyl alcohol), PVP, poly (vinyl pyrrolidone) -- RES reticuloendothelial system -- RGD arginyl-glycyl-aspartic acid sequence -- rGO reduced graphene oxide -- SAR specific absorption rate -- SBF simulated body fluid -- SEM scanning electron microscopy -- SL stereolithography -- SLP specific loss power -- SMNC shape memory nanocomposites -- SMP shape memory polymers -- SPIONs superparamagnetic iron oxide nanoparticles -- SPF silk fibroin protein -- TDLW two-photon direct laser writing -- TEM transmission electron microscopy -- TMDCs transition metal dichalcogenides -- TMEDA tetramethyl ethylenediamine -- TREG tri(ethylene glycol) -- TREM triethanolamine -- UV ultraviolet; Materials science -- Periodicals; Science des matériaux -- Périodiques; 620.1105
• DOI: 10.1016/j.pmatsci.2020.100742
• Languages: English
• ISSNs: 0079-6425

Abstract

Highlights: Magneto-responsive devices for cancer theranostics are reviewed. Magnetic nanoparticles are used for cancer diagnostic through MRI. Magnetic nanoparticles are clinically approved for magnetic hyperthermia application. 1D and 2D magnetic nanosystems have huge potential for cancer theranostics. 3D and 4D magnetic nanosystems still need further study and optimization. Abstract: Design, research, and development of new and improved smart multifunctional devices is one of the main topics in the advanced functional materials agenda for the next decade. Smart materials that can be triggered by external stimuli are seen with high potential for innovative treatments and improved drug delivery systems by regulatory agencies like the FDA and EMA. The incorporation of magnetic nanostructures into complex systems produces multifunctional devices that can be spatiotemporally controlled by an external magnetic field. These magneto-responsive devices can be used for a multitude of biomedical applications, from diagnostic to the treatment of tumors, and are actively being developed and tested for cancer theranostics. Herein, we review the development of magneto-responsive devices for cancer theranostics, starting from the most straightforward architecture, single nanoparticles. We give some theoretical concepts about the design and production of such systems while providing a critical review of applications in clinical practice. Naturally, the review evolves to more complex architectures, from one-dimensional to three-dimensional magneto-responsive systems, demonstrating higher complexity and multifunctionality, and consequently, higher interest for clinical practice. The review ends with the main challenges in the design and engineering of magneto-responsive devices for cancer theranostics and future trends in this biomedical field.