Copper‐catalyzed Reaction of Anthranils with Methyl Ketones: Site‐Selective C5‐Dicarbonylation of Anthranils. Issue 4 (23rd December 2020)

• Record Type: Journal Article
• Authors: Zhuang, Shi‐Yi; Tang, Yong‐Xing; He, Cai; Chen, Xiang‐Long; Xue, Wei‐Jian; Wu, Yan‐Dong; Wu, An‐Xin
• Is Part Of: Advanced synthesis & catalysis. Volume 363:Issue 4(2021)
• Page Start: 1137
• Page End: 1141
• Publication Date: 2020-12-23
• Subjects: copper-catalyzed -- site-selective -- Csp3-H/Csp2-H cross-coupling -- 1, 2-dicarbonyl compounds; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202001334
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A copper‐catalyzed site‐selective C5‐dicarbonylation reaction of anthranils has been developed for synthesis of 1, 2‐dicarbonyl compounds using methyl ketone as a commercially available carbonylation reagent. This process represents the first example to implement the C5‐dicarbonylation of anthranils, which involves an oxidative C sp 3 ‐H/C sp 2 ‐H cross‐coupling reaction along with thermolytic N−O bond cleavage. Abstract :