Association between rehabilitation during hospitalization and perinatal outcomes among pregnant women with threatened preterm birth. (3rd April 2021)

• Record Type: Journal Article
• Authors: Shigemi, Daisuke; Isogai, Shunsuke; Uda, Kazuaki; Aso, Shotaro; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 34:Number 7(2021)
• Page Start: 1028
• Page End: 1033
• Publication Date: 2021-04-03
• Subjects: Cesarean section -- physical therapy -- preterm birth -- rehabilitation; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2019.1623197
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Objective: This study conducted a nationwide retrospective cohort study to evaluate whether rehabilitation for pregnant women during long-term hospitalization is associated with adverse perinatal events. Methods: We performed a retrospective cohort study using a diagnosis procedure combination (DPC) database, a national inpatient database for acute-care inpatients in Japan. Hospitalized pregnant women diagnosed with threatened preterm birth, who stayed in the hospital for 7 days or longer from July 2010 to March 2017 in Japan were identified. One-to-four propensity score-matched analyses were performed to compare perinatal outcomes between patients with and without rehabilitation during hospitalization. The primary outcome was preterm birth (<35/0 weeks of gestation) during hospitalization. Results: Of the 141, 705 eligible patients, 351 (0.25%) received any type of rehabilitation during hospitalization. One-to-four propensity score matching created a rehabilitation group ( n = 338) and a nonrehabilitation group ( n = 1352). The propensity-matched analysis showed that the proportion of preterm births in the rehabilitation group was lower than that in the nonrehabilitation group (5.9% versus 8.9%; risk difference: −3.0%; 95% confidence interval (CI): −5.9 to −0.03). Conclusions: This retrospective nationwide study suggests that rehabilitation for hospitalized patients with threatened preterm birth may reduce the risk of preterm birth. Brief rationale: In this nationwide study, we suggest that rehabilitation for long-term hospitalized patients with threatened preterm birth may reduce the risk of preterm birth.