Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2. (February 2021)

• Record Type: Journal Article
• Authors: Ogilvie, B.H.; Solis-Leal, A.; Lopez, J.B.; Poole, B.D.; Robison, R.A.; Berges, B.K.
• Is Part Of: Journal of hospital infection. Volume 108(2021)
• Page Start: 142
• Page End: 145
• Publication Date: 2021-02
• Subjects: COVID-19 -- SARS-CoV-2 -- Coronavirus -- Disinfection -- Quaternary ammonium -- Hand sanitizer; Cross infection -- Periodicals; Cross infection -- Prevention -- Periodicals; Nosocomial infections -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Cross Infection -- Periodicals; Cross Infection -- prevention & control -- Periodicals; Infection Control -- Periodicals; Electronic journals; 614.44
• DOI: 10.1016/j.jhin.2020.11.023
• Languages: English
• ISSNs: 0195-6701

Abstract

Summary: Background: SARS-CoV-2 is the virus responsible for the current global pandemic, COVID-19. Because this virus is novel, little is known about its sensitivity to disinfection. Methods: We performed suspension tests against SARS-CoV-2 using three commercially available quaternary ammonium compound (Quat) disinfectants and one laboratory-made 0.2% benzalkonium chloride solution. Findings: Three of the four formulations completely inactivated the virus within 15 s of contact, even in the presence of a soil load or when diluted in hard water. Conclusion: Quats rapidly inactivate SARS-CoV-2, making them potentially useful for controlling SARS-CoV-2 spread in hospitals and the community.