'Posture second' strategy predicts disability progression in multiple sclerosis. (June 2021)

• Record Type: Journal Article
• Authors: Castelli, Letizia; Quartuccio, Maria Esmeralda; Ruggieri, Serena; De Giglio, Laura; Prosperini, Luca
• Is Part Of: Multiple sclerosis. Volume 27:Number 7(2021)
• Page Start: 1140
• Page End: 1144
• Publication Date: 2021-06
• Subjects: Multiple sclerosis -- balance -- cognitive-posture interference -- force platform; Central nervous system -- Diseases -- Periodicals; Myelin sheath -- Diseases -- Periodicals; Inflammation -- Periodicals; Multiple sclerosis -- Periodicals; Central Nervous System Diseases -- Periodicals; Demyelinating Diseases -- Periodicals; Inflammation -- Periodicals; Multiple Sclerosis -- Periodicals; Système nerveux central -- Maladies -- Périodiques; Gaine de myéline -- Maladies -- Périodiques; Inflammation (Pathologie) -- Périodiques; Sclérose en plaques -- Périodiques; Electronic journals; 616.834005
• DOI: 10.1177/1352458520963926
• Languages: English
• ISSNs: 1352-4585

Abstract

We assessed 168 patients with multiple sclerosis (MS) by force platform to obtain the dual-task cost (DTC) of balance, that is, the change in postural sway from quiet standing to dual-task condition (Stroop test). After a median follow-up time of 3.5 years from this assessment, disability progression occurred in 45 (27%) patients. Disability progression was predicted by the adoption of a 'posture second' strategy, that is, values of DTC of balance exceeding those obtained from 62 healthy controls, even after controlling by demographic and clinical characteristics. The DTC of balance may potentially represent a novel and easy tool to predict MS progression.