Palladium‐Catalyzed Reductive Carbonylation of (Hetero) Aryl Halides and Triflates Using Cobalt Carbonyl as CO Source. Issue 2 (22nd December 2020)

• Record Type: Journal Article
• Authors: Dogga, Bhushanarao; Kumar, C. S. Ananda; Joseph, Jayan T.
• Is Part Of: European journal of organic chemistry. Issue 2(2021)
• Page Start: 309
• Page End: 313
• Publication Date: 2020-12-22
• Subjects: Bimetallic catalyst -- Cobalt carbonyl -- Formylation -- Palladium -- Reductive carbonylation; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202001328
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: An efficient protocol for the reductive carbonylation of (hetero) aryl halides and triflates under CO gas‐free conditions using Pd/Co2 (CO)8 and triethylsilane has been developed. The mild reaction conditions, enhanced chemoselectivity and, easy access to heterocyclic and vinyl carboxaldehydes highlights its importance in organic synthesis. Abstract : A generalized protocol for the reductive carbonylation of (hetero) aryl halides and triflates under CO gas‐free conditions using Pd/Co2 (CO)8 and triethylsilane has been developed. The mild reaction conditions, enhanced safety, and wide substrate scope highlight its importance in routine organic synthesis.