Eosinophilic cellulitis successfully treated with Methotrexate. (25th June 2020)

• Record Type: Journal Article
• Authors: Yeon, Janice; Chan, Renee CF; Zagarella, Samuel
• Is Part Of: Australasian journal of dermatology. Volume 61:Number 4(2020)
• Page Start: e421
• Page End: e423
• Publication Date: 2020-06-25
• Subjects: corticosteroids -- eosinophilic cellulitis -- flame figures -- methotrexate -- Well syndrome; Dermatology -- Periodicals; Dermatology -- Australasia -- Periodicals; 616.5005
• DOI: 10.1111/ajd.13358
• Languages: English
• ISSNs: 0004-8380

Abstract

Abstract: Eosinophilic cellulitis is a rare inflammatory skin disease of unknown aetiology, first described by George Wells in 1971 as a recurrent granulomatous dermatitis with eosinophilia. It is typically characterised by recurrent pruritic erythematous plaques, vesicles or bullae usually involving the extremities and trunk. Many cases of eosinophilic cellulitis are difficult to treat and traditionally require long course of oral steroids, resulting in steroid side effects. This case adds to the literature in that we report the use of methotrexate to treat eosinophilic cellulitis, as a safe and efficacious therapeutic alternative.